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KMID : 0985420220440030181
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Laboratory Medicine and Quality Assurance
2022 Volume.44 No. 3 p.181 ~ p.184
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False Elevation of the Concentration of Thyroid- Stimulating Hormone: A Case Report
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Yoon Young-Ahn
Jeong Hwal-Rim
Choi Young-Jin
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Abstract
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Analytical errors owing to endogenous interfering substances may occur for some patient specimens. Interference can lead to false-positive or falsenegative results, or both, which may lead to a false diagnosis or inappropriate treatment. We report a case of false elevation of thyroid-stimulating hormone concentrations measured using an electrochemiluminescent immunoassay in a clinically euthyroid 10-year-old Korean boy with central precocious puberty. If the clinical presentations and test results of a patient are inconsistent, a clinician should suspect interference in clinical laboratory tests.
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KEYWORD
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Interference, Polyethylene glycols, Thyrotropin, Chemiluminescent measurements, Case report
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